Anybody’s/anyone’s guess Definition 1 of 1Pro Tip 1/3Uncertainty Expression Use it to express that the outcome of a situation cannot be predicted by anyone. Whether we'll have good weather on our trip is anybody's guess. Pro Tip 2/3Equal Ignorance Implies that no one has special knowledge about the subject in question. Who she'll choose as her dance partner is anybody's guess. Pro Tip 3/3Casual Context Best used in informal conversations rather than formal or academic writing. How long the meeting will last is anybody's guess.