Initially from video games, where it literally signals the end of play.

Gaming Origin

Used also outside gaming to mean an abrupt end.

Literal Use

Often referenced in pop culture, signaling a conclusion or failure.

Symbolizes an irrevocable end in non-gaming situations.

Implies that efforts have failed and there's no chance to recover.

Informal, may be inappropriate in formal or sensitive scenarios.

Used when a situation seems impossible to get better.

Expresses a feeling that there's no hope left.

Indicates a situation is seriously or irreversibly bad.