Indicates actions are driven by deep understanding and concern for another's needs. The charity workers have the community's interests at heart, always listening to their concerns.
Pro Tip 2/3
Personal Connection
Used when someone's care for others stems from a personal relationship, like family or friends. Despite his strict rules, Dad has our interests at heart.
Pro Tip 3/3
Sincerity Implied
The phrase suggests genuine concern, not just superficial care. You can trust her advice; she has your interests at heart.