In spite of something Definition 1 of 2Pro Tip 1/3Contrast Emphasis Use 'in spite of' to stress a contrast between expectations and reality. In spite of his fear of heights, he went skydiving. Pro Tip 2/3Unexpected Outcome Highlight outcomes that are surprising given the circumstances. In spite of being newcomers, they won the competition. Pro Tip 3/3Action Continuation Indicate that the action or situation continues despite obstacles. In spite of the delay, the project was completed on time.