Knock off Definition 1 of 4Pro Tip 1/3Casual speech Best used in casual conversation rather than formal situations. I'm going to knock off at 5 pm today. Pro Tip 2/3Not literal 'Knock off' doesn't mean to physically hit something when used in this context. Can we knock off discussing this and move on? Pro Tip 3/3Related to time Often refers to concluding work in relation to time, such as quitting time. What time do you usually knock off from work?