The phrase can imply strong feelings against something considered wrong or unjust. After the scandal, employees began to react against the company's policies.
Pro Tip 2/3
Group Dynamics
It's often used to describe collective opposition or a movement within a group. The community started to react against the new regulations.
Pro Tip 3/3
Personal Conflict
Can describe personal opposition, not just large-scale resistance. He decided to react against his friend's dishonest advice.