Resign yourself to Definition 1 of 2Pro Tip 1/3Emotional Acceptance Used when emotionally coming to terms with an unpleasant situation. After the accident, he resigned himself to a lengthy recovery. Pro Tip 2/3Inevitable Outcomes Used when acknowledging an outcome that is certain or unavoidable. With the deadline tomorrow, I've resigned myself to a sleepless night. Pro Tip 3/3Negative Connotation Usually implies disappointment or a sense of giving up on something better. She resigned herself to never fulfilling her dream of becoming an artist.