Scream out Definition 1 of 3Pro Tip 1/3Intense Emotion Use 'scream out' to express strong emotions during extreme situations. He screamed out in frustration when he missed the train. Pro Tip 2/3Urgent Appeal Often used when someone needs urgent help or is in danger. Lost in the woods, the boy screamed out for rescue. Pro Tip 3/3Unexpected Reaction Used when someone reacts abruptly, usually due to surprise or pain. She screamed out when she saw the spider on her bed.