Seize up Definition 1 of 3Pro Tip 1/3Sudden Failure Use 'seize up' to indicate an unexpected and complete stoppage of machinery. The printer seized up in the middle of printing my report. Pro Tip 2/3Technical Context 'Seize up' is often used when talking about technical or mechanical problems. During the flight, the drone's motor seized up. Pro Tip 3/3Not Always Literal Sometimes 'seize up' is used metaphorically to describe situations that grind to a halt. The negotiations seized up after the disagreement.