Split up Definition 1 of 3Pro Tip 1/3Relationship End Often implies a romantic or significant relationship ending. They chose to split up after years of constant arguing. Pro Tip 2/3Temporary Separation Can refer to a brief, physical separation in a group activity. Let's split up to cover more ground during the scavenger hunt. Pro Tip 3/3Emotional Weight Carries an emotional tone, suggesting some level of difficulty or sadness. It was hard for everyone when they decided to split up.