Take against Definition 1 of 1Pro Tip 1/3Unpredictable Change It emphasizes a sudden shift in feeling without clear justification. Everyone liked the new teacher until Jenna inexplicably took against her. Pro Tip 2/3Subjective Feeling Reflects a personal reaction, not based on objective facts. I don't know why, but I've taken against the idea of moving to that city. Pro Tip 3/3Emotional Impact Can indicate an emotional response that may affect relationships. After the argument, it seemed like she had taken against me.