The phrase originates from golf, where players begin by hitting the ball from a tee. She's excited to tee off at the charity golf event next weekend.
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Metaphoric Use
Used metaphorically to signify the start of various activities, not limited to sports. The mayor will tee off the city's centennial celebrations this Saturday.
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Specific Timing
Often used when specifying the exact time an event or action will begin. Our team will tee off the project planning session at exactly 9 AM.