Use when advising someone to make a smart decision based on available options. If you're debating between the train or bus, your best bet is the train for comfort.
Pro Tip 2/3
Cultural Usage
Commonly used in casual conversation, less formal but still acceptable in written English. For authentic cuisine, your best bet is the market downtown.
Pro Tip 3/3
Subtle Suggestion
Implies a recommendation rather than a command, making it a polite way to give advice. For a quiet evening, your best bet is the little café on the corner.