Tire out
Definition 1 of 1
Pro Tip 1/3Physical Activities
Often used after physical exertion, like sports or exercise. 
Running the marathon really tired me out.
Pro Tip 2/3Emotional Impact
Can describe mental fatigue due to stress or emotional events. 
Worrying about the exam all week has tired me out.
Pro Tip 3/3Parenting Context
Commonly used by parents describing their children's energy levels. 
It takes a lot to tire out my kids; they have so much energy.