Often used metaphorically to describe the exclusion of unsuitable elements from a situation or group. The company's tough interview process is designed to weed out unqualified applicants.
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Not Literal
Doesn't always involve physically removing something; it can be abstract, like ideas. The brainstorming session helped to weed out the less effective solutions.
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Negative Connotation
May imply that what is being removed is undesirable or not meeting certain standards. The new regulation helped to weed out corruption in the industry.