Wipe off Definition 1 of 3Pro Tip 1/3Physical Action Describes a physical movement of cleaning or clearing a surface by hand. He wiped off the whiteboard after the presentation. Pro Tip 2/3Not Just Cleaning Can refer to removing items from a surface as well as cleaning. She quickly wiped off the crumbs from the tablecloth. Pro Tip 3/3Often Immediate Used for actions that are prompt or soon after something has occurred. Wipe off the sauce from the stove while it's still fresh.