This phrase often shows frustration or resignation when effort doesn't lead to success. He practiced every day, but against the champions, he couldn't win.
Pro Tip 2/3
Express Difficulty
Use it when a task seems too difficult due to obstacles. With such a bad referee, our team can't win.
Pro Tip 3/3
Underdog Scenario
It's common to use when someone is at a clear disadvantage. With no previous experience, you can't win this chess tournament.