Use 'atonic' to describe extreme tiredness, much more than just being sleepy or lazy. He felt atonic after working three shifts back-to-back.
Pro Tip 2/3
Emotional Nuance
'Atonic' can imply a sense of helplessness or inability to act due to lack of energy. The news left her feeling suddenly atonic.
Pro Tip 3/3
Not Commonly Used
'Atonic' is not a word you'll hear often; it's more specific and less common than 'tired'. I only use 'atonic' for dramatic effect, like after running a marathon.