Use 'confute' to express a strong intellectual challenge to an idea or belief. The professor attempted to confute the notion that humans will never colonize Mars.
Pro Tip 2/3
Formal Contexts
Preferrably used in formal writing or discussions, not in casual conversations. In her thesis, she confuted prevailing misconceptions about renewable energy.
Pro Tip 3/3
Evidence Required
'Confute' implies that evidence or logical reasoning is provided to prove something wrong. The data gathered from the experiment confuted the scientist's initial hypothesis.