Hypertrophy/haɪˈpɜːrtrəfi/ Definition 1 of 2Pro Tip 1/3Medical Condition It often refers to an abnormal, excessive enlargement, commonly unhealthy. His arm showed hypertrophy due to his bone disease. Pro Tip 2/3Non-Gym Context Although linked with exercise, it's used in medical cases, not just for muscles. Adenoid hypertrophy can lead to breathing issues. Pro Tip 3/3Neutral Tone It's not a negative or positive word, but neutral, stating a fact about size. The doctor diagnosed him with liver hypertrophy.