Pigskin/ˈpɪɡskɪn/ Definition 1 of 2Pro Tip 1/3Sports Context Used to refer to the ball in American football, not soccer. They played a game with the pigskin during halftime. Pro Tip 2/3Informal Usage Casual expression, mainly used by sports fans or players. He can really throw the pigskin! Pro Tip 3/3American Football Commonly associated with North American culture due to the sport's popularity there. Watching them toss the pigskin is a Thanksgiving tradition.