Ramification/ˌræmɪfɪˈkeɪʃn/ Definition 1 of 2Pro Tip 1/3Action Link Think of 'ramification' as a chain reaction from a decision or action. Considering the possible ramifications, she decided to consult a lawyer. Pro Tip 2/3Often Negative 'Ramification' is frequently used to imply negative consequences. He didn't anticipate the severe ramifications of skipping class. Pro Tip 3/3Scope of Impact The impact of ramifications can range from personal to global scale. The environmental ramifications of deforestation are worldwide.