Salve/sæv/ Definition 1 of 3Pro Tip 1/3Health Context Used in medical or health settings to describe healing products. The nurse applied a salve to the burn. Pro Tip 2/3Topical Application Salve is a substance applied on the skin, not taken orally. Remember, the salve goes on the rash, not in your mouth. Pro Tip 3/3Not Just Medicine Though medical, salves can have natural or herbal ingredients. Her grandmother made a salve from garden herbs.