Sanctification/ˌsæŋktɪfɪˈkeɪʃn/ Definition 1 of 2Pro Tip 1/3Religious Ceremony Used when something is declared holy in a religious ritual. The sanctification ceremony for the new temple will take place next week. Pro Tip 2/3Cultural Context Used more in cultures with strong religious practices and language. Sanctification of the sacred relics is an annual event in our community. Pro Tip 3/3Physical Objects Often refers to making a physical space or item holy. The sanctification of the new icons will enhance the spiritual aura of the chapel.