Soulful/ˈsəʊlfl/ Definition 1 of 2Pro Tip 1/3Deeply Moving Use 'soulful' to describe experiences that touch people's emotions deeply. Her soulful rendition of the song brought tears to many. Pro Tip 2/3Artistic Expression 'Soulful' is often used to praise artists whose work shows great emotion. The painting had a soulful quality, evoking a sense of longing. Pro Tip 3/3Beyond Surface Soulful can imply depth and sincerity beyond just the surface of things. Despite his jokes, he has a surprisingly soulful perspective on life.