Sterility/stəˈrɪləti/ Definition 1 of 3Pro Tip 1/3Medical Context Use 'sterility' in discussions about health and reproduction. After years of trying, the diagnosis of sterility was devastating. Pro Tip 2/3Sensitive Topic Be cautious; 'sterility' can be a sensitive subject for many people. They discussed sterility with great care to not upset their friends. Pro Tip 3/3Not Gender-Specific 'Sterility' can refer to both males and females, not restricted to one gender. Both male and female sterility can impact a couple's plans.