Stupefaction implies a strong, overwhelming reaction, stronger than surprise or confusion alone. The magician's act left the audience in stupefaction.
Pro Tip 2/3
Not Literal
Stupefaction is used figuratively to express a metaphorical 'stunning' of the mind, not a physical effect. Her betrayal filled him with stupefaction.
Pro Tip 3/3
Unexpected Events
Stupefaction often results from events that are completely unexpected or difficult to comprehend. The sudden collapse of the building threw the onlookers into stupefaction.