Refers to a body's weak defense against illnesses or conditions. Due to his susceptibility, he avoided crowded places during flu season.
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Negative Connotation
Usually suggests a disadvantage or a propensity to negative outcomes. The plant's susceptibility to frost damage made it unsuitable for cold climates.
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Context Specific
Its meaning can change based on the context; could relate to health, emotions, etc. The country's economic susceptibility left it vulnerable to the global financial crisis.