The word 'vitiate' usually suggests harm or corruption, giving a negative tone. A single mistake may vitiate the entire research project.
Pro Tip 2/3
Intensity
'Vitiate' implies substantial harm rather than a minor issue. Overcooking the vegetables vitiated their nutritional value.
Pro Tip 3/3
Not Physical Damage
'Vitiate' often refers to abstract concepts, like processes or conditions, not physical objects. Lack of evidence could vitiate the credibility of his testimony.