Wiseacre/ˈwaɪzeɪkər/ Definition 1 of 1Pro Tip 1/3Colloquial Usage Used in casual or informal conversation, not in formal writing or speeches. My uncle always plays the wiseacre at family gatherings. Pro Tip 2/3Mild Disapproval Suggests annoyance but is not extremely offensive. The teacher wasn't amused by the wiseacre interrupting the class. Pro Tip 3/3Not Actual Wisdom Implies a lack of real knowledge or wisdom; sarcastic in tone. He's always acting like a wiseacre, but he rarely knows the answer.