Agonize/ˈæɡənaɪz/ Definition 1 of 3Pro Tip 1/3Emotional Weight Indicates not just concern but deep emotional struggle. I agonized over the eulogy I had to give. Pro Tip 2/3Extended Suffering Often implies a long duration of distress, not a quick decision. She agonized over the choice for weeks. Pro Tip 3/3Serious Decisions Used mainly for significant, life-changing decisions or concerns. He agonized over his vote in the election.