Aspirin/ˈæsprɪn/ Definition 1 of 2Pro Tip 1/3Pain Relief Aspirin is often mentioned when talking about relieving minor pain or discomfort. After spraining her ankle, Jenny asked for an aspirin. Pro Tip 2/3Common Medicine Aspirin is widely recognized and available over the counter in many drug stores. I picked up a bottle of aspirin from the pharmacy. Pro Tip 3/3Not For Children Use of aspirin isn't advised for children due to the risk of Reye's syndrome. The doctor recommended children's ibuprofen, not aspirin.