Atrophy/ˈætrəfi/ Definition 1 of 2Pro Tip 1/3Non-medical Usage Used metaphorically to describe neglect in various contexts, not only physical. His passion for painting atrophied after years in a stressful job. Pro Tip 2/3Emotional Impact Conveys a sense of loss or deterioration; may evoke sympathy or concern. Without practice, her singing voice atrophied, which saddened her fans. Pro Tip 3/3Gradual Process 'Atrophy' implies a slow decline, not something that happens suddenly. Neglected friendships may atrophy over years of disconnection.