Cocaine/kəʊˈkeɪn/ Definition 1 of 1Pro Tip 1/3Illegal Substance Cocaine is an illegal drug in most countries and is heavily penalized. He faced severe penalties after being caught with a bag of cocaine. Pro Tip 2/3Health Risk Cocaine has severe health risks including addiction and overdose. Many people die each year due to cocaine overdoses. Pro Tip 3/3Connotation Cocaine often carries connotations of a party drug among the wealthy or famous. Tabloids splashed headlines about the actor's cocaine-fueled parties.