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Debilitate

usgb/dɪˈbɪlɪteɪt/Volume
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Severity ImpactPlay
Debilitate implies a serious weakening effect, not just a slight hindrance. SlideThe invasive species has debilitated the local ecosystem.
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Extended EffectPlay
Use 'debilitate' to express a long-term or progressive weakening, rather than a temporary one. SlideYears of neglect have debilitated the infrastructure of the town.
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Total IncapacitationPlay
It can imply reducing strength to the point of near incapacitation, not just lessening it. SlideWithout its leader, the movement was debilitated.