Deplete/dɪˈpliːt/ Definition 1 of 2Pro Tip 1/3Resource Context Use 'deplete' when discussing usage of natural resources or supplies over time. Overfishing can deplete fish populations in the ocean. Pro Tip 2/3Not Instant 'Deplete' suggests a gradual process, not an immediate disappearance of something. Frequent withdrawals will gradually deplete your savings. Pro Tip 3/3Economic Terms Often used in economic and financial contexts to discuss diminishing assets or funds. The expensive lawsuit could deplete the company's capital.