Deranged/dɪˈreɪndʒd/ Definition 1 of 2Pro Tip 1/3Mental state Refers to someone's unstable or disordered mind, often associated with dangerous behavior. The movie portrayed the villain as a deranged genius. Pro Tip 2/3Negative connotation Using 'deranged' suggests a judgment or stigma towards mental health, use with sensitivity. The character's deranged actions made everyone uneasy. Pro Tip 3/3Intensely irrational Describes behaviors or thoughts that are wildly unreasonable or illogical. His deranged ideas about reality concerned his friends.