Differentiate/ˌdɪfəˈrenʃieɪt/ Definition 1 of 4Pro Tip 1/3Subtle Distinctions Uses skill to highlight minor or intricate differences often overlooked. A connoisseur can differentiate nuances in wine flavors. Pro Tip 2/3Not Just Visual Applies to senses beyond sight, like taste, sound, or touch. Chefs differentiate spices by their unique tastes. Pro Tip 3/3Emotional Nuance Can refer to discerning different feelings or attitudes. She could differentiate his mood by his tone of voice.