Dimple/ˈdɪmpl/ Definition 1 of 3Pro Tip 1/3Positive Connotation In many cultures, cheek dimples are considered attractive and a sign of good luck. Her dimples are so cute, they light up her face! Pro Tip 2/3Emotional Expression Dimples often appear when someone smiles, and they can make the expression seem more genuine. His dimples pop out whenever he's genuinely happy. Pro Tip 3/3Familial Trait Dimples can be a genetic trait, so they might run in families. Both siblings have deep cheek dimples like their mother.