Granddaughter/ˈɡrændɔːtər/ Definition 1 of 1Pro Tip 1/3Family Tree Understand where 'granddaughter' fits in a family tree to clarify relationships. In our family tree, Lucy is the youngest granddaughter. Pro Tip 2/3Term of Endearment 'Granddaughter' often implies affection; it's used lovingly by grandparents. My darling granddaughter, you make us so proud. Pro Tip 3/3Specific Descendant The term specifically refers to a female descendant in the second degree. Marta has two grandsons and one granddaughter.