Hex/heks/ Definition 1 of 4Pro Tip 1/3Negative Connotation Hex has a negative meaning, implying intentional harm or bad luck wishing. She avoided the old mansion, fearing the hex that locals talked about. Pro Tip 2/3Cultural Beliefs Use 'hex' to refer to superstitious practices or beliefs, common in folklore. In the village, wearing a blue amulet is said to ward off a hex. Pro Tip 3/3Informal Usage Using 'hex' in everyday conversation can sound informal or humorous. My computer keeps crashing; it's like it's got a hex on it!