Homo/ˈhəʊməʊ/ Definition 1 of 2Pro Tip 1/3Scientific Usage Used in biology to classify humans and related species; not for general human reference. In my anthropology class, we studied Homo erectus. Pro Tip 2/3Latin Origin It's a Latin word meaning 'man'; often used in scientific Latin phrases. Homo neanderthalensis lived 400,000 years ago. Pro Tip 3/3Not Interchangeable Don't confuse with 'Homo sapiens', which specifically refers to modern humans. Homo is the genus, but only Homo sapiens are us!