Milton Friedman

The most important ways in which I think the Internet will affect the big issue is that it will make it more difficult for government to collect taxes.

American Economist

Leonardo DiCaprio

Raising awareness on the most pressing environmental issues of our time is more important than ever.

American Actor

Prabhas

Friendship is a personal issue, and it should remain that way.

Indian Actor

Kimberly Elise

Self-esteem is such a challenging issue for young women.

American Actress

Whoopi Goldberg

For some reason, all artists have self-esteem issues.

Sally Field

You can't help but feel all the human-rights issues.

Judy Blume

I don't do issue writing. I do character writing.

American Author

Jagmeet Singh

I've never been afraid of taking on issues.

Canadian Lawyer

Kinky Friedman

American Singer

Steve Lukather

American Musician

Consider 'issue' to indicate matters of varying sizes, not just major problems.

Scope of Issue

'Issue' doesn't necessarily imply urgency; context will influence the severity.

Issue vs. Urgent

Using 'issue' can be a softer, less confrontational way to discuss problems.

Emotional Weight

'Issue' implies an organized, systematic distribution rather than a random one.

Planned Process

When items are 'issued', it's often by an authority like a government or organization.

Official Handling

When referring to publications, 'issue' signifies a single, repeatable release.

Periodic Publication

Issues of magazines or comics can be collectibles, with some editions being rare.

Collectable Nature

An 'issue' of items like stamps ensures they are identical and part of a set.

Uniformity in Items

Items like currencies are often 'issued' at specific times to replace old versions.

Timed Release

'Issue' can signify granting of official documents, confirming authenticity or validity.

Formal Authentication

 every major scientific organization in the world has concluded that the crops currently on the market are safe to eat and that the process of genetic engineering is no more risky than older methods of genetic modification. These are precisely the same organizations that most of us trust when it comes to other important scientific issues

Pamela Ronald: The case...

 of some of its original healthy function, depending on the severity of the initial wound and on the function itself. But because the skin does not fully recover, scarring continues to be a major clinical issue for doctors around the world. And even though researchers have made significant strides in understanding the healing process,

How a wound heals itself...

 comes with a high cost. As for the question of running out of space, the issue isn't so much about total land in the world as it is that large populations cluster together within cities. Most of the big cities in the world may run out of suitable burial grounds within a century.

What happens to our...

 have been crafted to appeal to you and affect your behavior, as have the soundbites and talking points of political campaigns which rarely present the most nuanced perspective on the issues. And the way that we use ready-made phrases and responses gleaned from media reports

What "Orwellian" really...

 The court issues binding decisions that each member state must comply with. Human rights law is constantly evolving as are our views and definitions of what the basic human rights should be. For example, how basic or important is the right to democracy or to development?

What are the universal...

 floor and more and more climate change for instance is becoming a really massive issue a lot of deep sea animals are um they're called stenotherms and it means they live within a very small temperature range and so any increases to temperature even

The Astronaut of the...

 so if any of you have a health issue that you need to deal with or a life change you need to deal with i urge you to imagine your healthy future self and start living that life now break your journey down into little battles you can win

The psychological weight...

 Some of the most influential mathematicians and scientists of all of human history have chimed in on the issue as well, often in surprising ways. So, is mathematics an invention or a discovery? Artificial construct or universal truth?

Is math discovered or...

 if they're on a shelf, the U.S. EPA warns against eating food off of them. Though we still occasionally run into issues with synthetic food dyes, our scientific understanding has helped us prune hazardous colors out of our lives.

History’s deadliest...

 land and plenty of water and this potential although having said that it had a very sad history when it comes to today issue of food security but as potential has attracted farmers like