Knot/nɑːt/ Definition 1 of 5Pro Tip 1/2Physical Action Knots involve specific hand movements and are physical; think 'twist' and 'pull'. She learned to knot balloons into animals. Pro Tip 2/2Secure and Tighten 'Knot' usually means to make something more secure by tying. He knotted the bag tightly to avoid spills.