Lonesome/ˈləʊnsəm/ Definition 1 of 3Pro Tip 1/3Emotional Weight Lonesome implies more sadness and emotional pain than simply being alone. The holidays can feel lonesome for those away from family. Pro Tip 2/3Subjective Feeling Being lonesome doesn't always mean nobody's around; it's about the feeling of missing company. She felt lonesome in the crowded room. Pro Tip 3/3Not Always Negative Occasionally, 'lonesome' implies peace and quiet away from others. He enjoyed his lonesome walk on the beach.