Prayer/prer/ Definition 1 of 4Pro Tip 1/3Religious Context Used in spiritual or religious discussions and involves reverence and is often solemn. They shared a prayer before the religious meal. Pro Tip 2/3Not Just Christian 'Prayer' is universal across many religions, not exclusively pertaining to Christianity. The imam led the prayer in the mosque. Pro Tip 3/3Personal Connection Often indicates a personal, intimate conversation or request directed at a higher power. His nightly prayer is a quiet time for reflection.