Profound/prəˈfaʊnd/ Definition 1 of 4Pro Tip 1/3Extent of Effect Use 'profound' to describe something with a significant and widespread impact. His innovation had a profound effect on the industry. Pro Tip 2/3Emotional Depth 'Profound' can express deep emotions or a strong, often soul-stirring, experience. She felt a profound sense of loss. Pro Tip 3/3Not Surface Level Indicates that the greatness or importance is not superficial but very deep and substantial. The book offers profound insights into human behavior.