Serene/səˈriːn/ Definition 1 of 3Pro Tip 1/3Nature Descriptions Use 'serene' to describe natural settings that are very calm and soothing. The serene forest's quietude brought peace to my heart. Pro Tip 2/3Emotion Tone 'Serene' also describes an emotional state suggesting free from stress. She spoke in a serene voice that calmed everyone in the room. Pro Tip 3/3Not Just Quiet 'Serene' goes beyond quiet to imply a deep, blissful peace. Even with silent waters, the ocean's vastness felt uniquely serene.