
Systemic
Bodywide Impact
Use 'systemic' to describe something that impacts the entire body or an entire system, not isolated parts.

Smoking has systemic effects on health.
Not Just External
'Systemic' implies the problem is embedded within the system itself, often internal and not just superficial.

His symptoms suggested a systemic infection rather than a localized one.
Compare with
ComprehensiveGlobalHolisticIntegrateRadicalThoroughUniversal
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