Unnerve/ˌʌnˈnɜːrv/ Definition 1 of 1Pro Tip 1/3Negative Emotion Unnerve typically implies causing anxiety, fear, or loss of confidence. The thought of public speaking unnerves me. Pro Tip 2/3Sudden Impact The effect described by 'unnerve' usually happens quickly and unexpectedly. An unexpected noise in the dark room unnerved her. Pro Tip 3/3Psychological Effect Use 'unnerve' to describe a mental or emotional impact, rather than a physical one. The intense gaze of the interviewer unnerved the candidate.